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Biomolecular shifts occur in our 40s and 60s (2024)

(med.stanford.edu)
170 points fzliu | 1 comments | 27 Jun 25 03:51 UTC | HN request time: 0.233s | source
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riskassessment ◴[27 Jun 25 04:36 UTC] No.44393737[source]▶
If you throw some data at a clustering algorithm, the clustering algorithm is guaranteed to give you clusters back. So I'm not convinced about the results suggesting a precise pattern of rapid aging.
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bboygravity ◴[27 Jun 25 06:25 UTC] No.44394176[source]▶
Are you at or over 40?

Anecdotally I feel I noticed a very fast ageing speed between 38 and 40. Suddenly got white hairs, feel more tired, more wrinkles, way harder to keep VO2max up (I run a lot), muscle sores after training suddenly lasting up to 3 days instead of 1, face looks older, etc.

I feel like that all happened real fast around this age.

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1. riskassessment ◴[27 Jun 25 13:15 UTC] No.44396571[source]▶
I said I was skeptical of there being a precise pattern of rapid aging. I never said I was skeptical that rapid/non-linear aging can occur. If you did experience rapid aging in the way the paper measured this from 38-40 that is more evidence in support of my point that there is some broad random distribution of when rapid aging occurs and this paper and blog post overintepret the data to mean rapid aging occurs precisely in your mid-forties and at 60.