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Biomolecular shifts occur in our 40s and 60s (2024)

(med.stanford.edu)
170 points fzliu | 1 comments | 27 Jun 25 03:51 UTC | HN request time: 0.311s | source
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riskassessment ◴[27 Jun 25 04:36 UTC] No.44393737[source]▶
If you throw some data at a clustering algorithm, the clustering algorithm is guaranteed to give you clusters back. So I'm not convinced about the results suggesting a precise pattern of rapid aging.
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bboygravity ◴[27 Jun 25 06:25 UTC] No.44394176[source]▶
Are you at or over 40?

Anecdotally I feel I noticed a very fast ageing speed between 38 and 40. Suddenly got white hairs, feel more tired, more wrinkles, way harder to keep VO2max up (I run a lot), muscle sores after training suddenly lasting up to 3 days instead of 1, face looks older, etc.

I feel like that all happened real fast around this age.

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1. astura ◴[27 Jun 25 12:41 UTC] No.44396353[source]▶
I'm well into my 40s. I've noticed aging in almost all my friends and work colleagues my age as well as those up to 10 years younger than me. I haven't noticeability aged myself yet though. Don't have any grey hairs, no wrinkles, don't look older than I did in my 20s.

It's not just my perception either, other people assume I'm early 20s.

I can't really relate to the physical stuff though because muscle sores after training was always 3 days for me and it was always difficult to keep VO2max up, even in my early teens. So I guess I just started out in middle age.