Biomolecular shifts occur in our 40s and 60s (2024)

If you throw some data at a clustering algorithm, the clustering algorithm is guaranteed to give you clusters back. So I'm not convinced about the results suggesting a precise pattern of rapid aging.

Are you at or over 40?

Anecdotally I feel I noticed a very fast ageing speed between 38 and 40. Suddenly got white hairs, feel more tired, more wrinkles, way harder to keep VO2max up (I run a lot), muscle sores after training suddenly lasting up to 3 days instead of 1, face looks older, etc.

I feel like that all happened real fast around this age.

I'm 38. We had three kids over a period of 8 years. Looking at old pictures I seemingly held on for a long while, until something hit me at 35-36?!

It's like there's two versions of me now, the one who was somehow moderately fit by biochemical decree, with a healthy amount of flesh to his face, voluminous dark blonde hair and a pleasant complexion...

... And the grey haired, weathered, lined, dessicated mummy I see in the mirror. I love my kids dearly but the constant caring really takes something out of you. That and the whole getting older thing in TFA.

I keep telling myself I'll get a gym membership soon to reclaim some of my dignity.

Exercise is not optional.

Go for it!

And try not to be in the majority group of gym goers who pay the membership without attending ;)

Exactly. As a regular at a non-hardcore gym, I had never appreciated it until I saw the gym sell 12mo membership for the price of 4x 1mo, and then I tried to remember how many people sticked around for a meaningful period. Very few men. No women.

The nearest gym is truly the best gym for 90% of people, as everyone seems to look for excuses not to go. So just go, people there will not bite you or shame you.