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170 points fzliu | 1 comments | | HN request time: 0.299s | source
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nakedneuron ◴[] No.44394139[source]
Truth is many people also stop moving (exercising) significantly in their forties (reason being probably sitting lifestyle promotes posture and fascia degradation which makes moving less and less enjoyable).

I'd posit that another significant decline in moving occurs in the sixties when many go in rent.

Not sure if the biological clock is cause of abrupt changes or rather our scheduled lives. So, no significant changes from the sixties on? Then what's the genetic function of those programmations?

People who reach old age (100+) are mostly also comparatively healthy.

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nurettin ◴[] No.44394217[source]
> people also stop moving (exercising) significantly in their forties

Also likely that people who never experienced the negative outcomes of a sedentary or unhealthy life style start doing so due to the biomolecular changes. Drinking more likely to hurt your liver, soda more likely to cause diabetes, smoking more likely to cause cavities despite having done all that for 20 years without visible problems.

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1. gspetr ◴[] No.44394462[source]
>20 years without visible problems.

Even with the most charitable steelman interpretation of "visible problems", 2 out of 3 things you've listed have strong evidence for being responsible for weight gain, and even smoking has some weaker evidence supporting it.