For decades now I have been using RAM (mfs, tmpfs) as "disk", i.e., boot from USB, no internal HDD, no internal SSD.^1 Entire OS fits in memory. When compiling OS userland there is simply no comparison; disk is painfully slow. I am not a gamer. I use RAM as a filesystem and workspace. I just got another computer with 64GB RAM. I will get 96GB or more when price comes down.
1. I use removable, external drives for anything I want to save long-term. No "cloud" storage.