From the Introduction [1]
Many container platforms are available, but Apptainer is focused on:
Verifiable reproducibility and security, using cryptographic signatures, an immutable container image format, and in-memory decryption.
Integration over isolation by default. Easily make use of GPUs, high speed networks, parallel filesystems on a cluster or server by default.
Mobility of compute. The single file SIF container format is easy to transport and share.
A simple, effective security model. You are the same user inside a container as outside, and cannot gain additional privilege on the host system by default. Read more about Security in Apptainer.
[1]
https://apptainer.org/docs/user/main/introduction.html