I often think about how cold our lifeforms on earth are, relative to temperatures of things in the universe. 0 Kelvin is theoretical lowest possible temp, quasars are apparently > 10 trillion Kelvin (10,000,000,000,000K), yet all life we know of is between what, 250K and 400K?
Well, lifeforms on earth are all pretty dependent on being water based, and water in the liquid state specifically. Maybe there is a possibility of exotic life based on some other types of chemistry and/or phases of matter. But the fact that earth happened to form in this particular goldilocks zone for water-based life is probably why that's the only life we can see for now.