I'm in ML-land. I thought we were all hopelessly tied to conda. But I moved all my own projects to uv effortlesly and have never looked back. Now first thing I do when pulling down another reseacher's code is add a pyproject toml (if they don't have one), `uv add -r`, and `uv run` off into the sunset. I especially like how good uv is with non-pypi-published dependencies: GitHub, dumb folders, internal repos, etc.