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1163 points jbredeche | 2 comments | | HN request time: 0.455s | source
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tuna-piano ◴[] No.44000717[source]
If someone in the year 2050 was to pick out the most important news article from 2025, I won't be surprised if they choose this one.

For those who don't understand this stuff - we are now capable of editing some of a body's DNA in ways that predictably change their attributes. The baby's liver now has different (and better) DNA than the rest of its body.

We still are struggling in most cases with how to deliver the DNA update instructions into the body. But given the pace of change in this space, I expect massive improvements with this update process over time.

Combined with AI to better understand the genome, this is going to be a crazy century.

Further reading on related topics:

https://www.lesswrong.com/posts/JEhW3HDMKzekDShva/significan...

https://www.lesswrong.com/posts/DfrSZaf3JC8vJdbZL/how-to-mak...

https://www.lesswrong.com/posts/yT22RcWrxZcXyGjsA/how-to-hav...

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rob74 ◴[] No.44001456[source]
That's all very cool, but there are also articles like this one: https://www.theguardian.com/us-news/2025/feb/20/trump-nih-cu... - I'm not able to read the Times article because it's paywalled, but as other commenters have mentioned, this research was funded by the NIH, which the Trump administration is currently in the process of defunding. So, if further progress along this road will be made, it'll probably be much slower and less likely to be in the US.
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1. cnity ◴[] No.44003033[source]
Or, it means that funding will be secured in the private sector. Basically by investors that focus on revenue streams (read: extremely expensive private healthcare).
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2. rob74 ◴[] No.44007985[source]
Yeah, maybe for stuff like this which (now) has direct applications, yes. But for basic research (and it took decades of basic research on genetics, gene editing etc. etc. to get to this point)? No way...