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Baby is healed with first personalized gene-editing treatment

(www.nytimes.com)
1163 points jbredeche | 1 comments | 15 May 25 18:06 UTC | HN request time: 0s | source
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palisade ◴[16 May 25 05:32 UTC] No.44002113[source]▶
Does this mean when they grow up, their own offspring will also have this defect and require a correction? And, if so, does this mean it is now introducing this defective gene into our gene pool?

I know this is an issue with caesarean section. It is becoming more prevalent because those who require it are surviving, making it more likely to happen in their offspring.

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mondaygreens ◴[16 May 25 05:48 UTC] No.44002183[source]▶
How can they pass it on when they don't have the defect any more?
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1. nahsra ◴[16 May 25 06:01 UTC] No.44002241[source]▶
Gene editing is still pretty crude in terms of delivery.

Just because you can hit some germ-line cells in the liver, for example, doesn’t imply you’ll have good penetration into the reproductive organs.

We can’t zap people and change all their DNA at once, unless we can intervene at the point it’s just a few cells.