There's usually indirect reproduction. For instance I can take some principle from a study and integrate it into something else. The real issue is that if the result is negative - at least from my understanding - the likelihood of publication is minimal, so it isn't communicated. And if the principle I've taken was at fault there's a lot of space for misattribution, I could blame a litany of different confounders for failures until, after some
long while I might decide to place blame on the principle itself. That itself may require a complete rework of any potential paper, redoing all the experiments (depending on how anal one is in data collection).
Just open up a comment section for institutional affiliates.