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Adipose tissue retains an epigenetic memory of obesity after weight loss

(www.nature.com)
263 points paulpauper | 1 comments | 14 Apr 25 04:47 UTC | HN request time: 0.279s | source
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paulpauper ◴[17 Apr 25 07:33 UTC] No.43714036[source]▶
The more you research/learn about obesity, the worse it is, much like smoking. One of the most depressing stats is that dieting does not get easier with time. The probability of eventually regaining all the weight eventually converges to 100%. Even if you're successful for 2 years, people still regain by year 4, 5, etc. The body never resists trying to regain the weight. GLP-1 drugs are the best hope yet.
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agos ◴[17 Apr 25 08:14 UTC] No.43714260[source]▶
absolutely. and yet people will still say "just eat less"! Imagine telling a person who smokes "just smoke less"
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1. kbelder ◴[18 Apr 25 21:25 UTC] No.43731997[source]▶
That is the key to stopping smoking.

Telling them they can't possibly smoke less through willpower is incredibly harmful. Same with eating.