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Adipose tissue retains an epigenetic memory of obesity after weight loss

(www.nature.com)
263 points paulpauper | 1 comments | 14 Apr 25 04:47 UTC | HN request time: 0.22s | source
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spoiler ◴[17 Apr 25 06:53 UTC] No.43713850[source]▶
As someone who's struggled with weight loss, and have known others to struggle with it well, I think we colloquially called this "slow metabolism".

It always did feel like it was easier to gain weight than lose it, especially fat weight and not muscle weight for me.

I was recently sent a video about fat adaptation (basically teaching your body to be better at burning fat) by a very fit friend, but I wonder how much of that is bro science and how much of it is grounded in reality. Maybe worth looking into more deeply if it can counteract or balance out this.

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e40 ◴[17 Apr 25 13:41 UTC] No.43716696[source]▶
For me, sugar was the reason I couldn't lose weight. I got a CGM (continuous glucose monitor) and got my blood sugar under control, and with very little effort I lost a lot of weight.

I use 90% cacao Lindt to control my sweet tooth. 1/2 the bar has 4g of sugar, and I consume it over hours. It also has the side effect of reducing my hunger. If you eat much of 90% chocolate, it makes you feel nausea. The trick is to put a small chip in your mouth and let it melt. It's quite delicious and I've not had any sweets in 80+ days.

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1. autoexec ◴[18 Apr 25 06:58 UTC] No.43725703[source]▶
I'm a chocolate fan myself and it was something I used to buy often, but just as I started getting into the hard stuff (80% or higher) I learned about all the problems with heavy metals in dark chocolate and specifically in Lindt, and then later learned about the use of child slaves which is an industry wide issue and not exclusive to Lindt/Russell Stover/Ghirardelli/Lindor although Lindt and Hershey are reportedly worse than other brands.

You can find brands that claim to be more ethical in terms of sourcing their cocoa, but the smaller brands that do are also less likely to have been tested for heavy metals.

While it's unclear how harmful the heavy metals would be to me specifically at the amounts I was eating, the whole thing kind of put me off chocolate in general and dark chocolate in particular. I rarely have it anymore.