Adipose tissue retains an epigenetic memory of obesity after weight loss

I've been wondering about that. Like all cosmetic surgery liposuction is looked down upon.

But maybe it can also be a useful and healthy weight loss strategy?

Despite being looked down on, it's still very common. I know several people who have had liposuction. The results are only temporary. Everyone I know that has had this procedure has rebounded back to their original body weight within 2 years.

Liposuction is actually a very risky procedure, at least in relation to its benefits. For example, fat embolisms in liposuction occur in 8-9% of patients that undergo the procedure. There are other risks that are non-trivial as well.

If I had to advise a patient on whether they should consider liposuction vs gastric bypass vs GLP1R agonists, I would tell them to not consider liposuction in that equation at all.

As with most cosmetic surgery, risks like these are downplayed by practitioners (willfully and otherwise) as well as by people in these social media circles.

This doesn't mean liposuction shouldn't ever be used, however. It can have good uses in reconstructive surgery, for example, where fat is sucked up to be used in reconstructing a different area. In this case, the potential reduction in morbidity and restoration of function to the patient, or increasing their autonomy, might make the risks associated with lipo worth it.