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112 points wglb | 1 comments | | HN request time: 0.202s | source
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idontwantthis ◴[] No.43683040[source]
Any idea if this protein has any relation with seratonin? Could the effect of SSRIs be related in any way?
replies(7): >>43683081 #>>43683135 #>>43683263 #>>43683632 #>>43683839 #>>43683863 #>>43684615 #
1. FollowingTheDao ◴[] No.43684615[source]
Yes, cytokine like IL 17 increase an enzyme called IDO which pulls tryptophan away from the serotonin production pathway.

https://www.researchgate.net/figure/Effect-of-IDO-on-seroton...