Plain – a web framework for building products with Python

I think to really learn Python for web as a developer you really have to learn WSGI/Gunicorn/etc and handling sessions within this.

I’ve found the challenge with Python for web is deployment as most website deployments are geared towards serverless workers or cdn’d javascript bundles and most python systems use WSGI and sessions, which is fundamentally different and the biggest challenge in newbie’s using python for websites.

If you're building your own framework and server, then yes. Otherwise, all major frameworks handle the communication with uwsgi, etc and you can treat them as a blackbox. Any other setup in-between (like nginx -> uwsgi) is boilerplate stuff easily found in tutorials or LLM chat.