I have always wondered why DNA is an accepted evidence. It's so easy to contaminate a crime scene or bring someone else hair, skin cells, etc by mistake.
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In reality, criminals are angry, frightened, in a rush, high or stupid, and they make the most elementary mistakes, so DNA and fingerprints work just fine almost all the time. In like 99% of cases there's not much doubt about who did it, the main thing is to have a watertight case against them when they deny it.
Framing someone else is not a perfect crime. A perfect crime finds no criminal, accused or convicted.
Rule 43(a) in the criminal procedures handbook IIRC.