A touchpad seems to really cripple the gameplay -- one idea could be to ask what device players are using and make slight adjustments. For touchpads, moving the cursor is slower, and the drag-pull mechanism doesnt really work -- and its easy to misclick a drag.
Some rougelike mechanics would also make it possible to naturally level the gameplay -- ie., the more failures a person has the more metaprogression they get, so worse players unlock a natural easy mode.
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