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My 16-month theanine self-experiment

(dynomight.net)
817 points dynm | 2 comments | 09 Mar 25 03:08 UTC | HN request time: 0.418s | source
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jaggederest ◴[09 Mar 25 05:38 UTC] No.43306580[source]▶
This is actually a thing I wish existed, but I don't have time and energy to make it right now. I'd pay $25 a month or more.

Basically it's an application that lets you do self-experiments like this, properly blinded and with good statistics. A challenge-dechallenge-rechallenge study is one of the ones I like, but if you want to do one you essentially have to design the study anew each time, and it would be convenient to run multiple at once if that's possible.

I'm not interested in generalizing, I just want to know if (for example) taking Vitamin D every day at 1000 iu is enough, or whether I should be taking more or less. I can get labs done on this, of course, but again I'm more interested in subjective wellbeing than blood levels beyond avoiding deficiency or hypervitaminosis.

Maybe such an app exists and I simply don't know about it.

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1. npunt ◴[09 Mar 25 06:48 UTC] No.43306854[source]▶
I've been thinking the same thing! The app should have protocol templates for whatever intervention I'm testing, what outcomes I should track, and what confounds might be. And if it isn't part of the templates, help me develop the protocol, including being able to set what level of confidence I want. It should tell me what actions I should take to improve confidence (e.g. bloodwork). It should hide the results from me until the overall intervention is complete.

All the other health apps and tracking systems I've seen are operating at one level of abstraction too low (just the data itself and its direct insights), or try to find patterns from p-hacking passive signals (it looks like when you work out you sleep better, did you know your HRV is 1.1 higher when you do [unrelated thing]). There's no buy-in or sense of direction in these products, no pushing me to do more to acquire data, no laser focus on a targeted test / intervention.

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2. davidanekstein ◴[09 Mar 25 11:40 UTC] No.43308180[source]▶
I made an app for this called Reflect [1]. There aren’t templates yet but you can run self guided experiments for anything you can model as a metric in the app. I just wrote about an experiment I did with nootropic coffee [2]. I think you have a point about sense of direction and premade templates being targeted and useful. Reflect is very much generic and untargeted.

[1] https://apps.apple.com/us/app/reflect-track-anything/id64638...

[2] https://open.substack.com/pub/reflectapp/p/my-experience-wit...