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My 16-month theanine self-experiment

(dynomight.net)
817 points dynm | 2 comments | 09 Mar 25 03:08 UTC | HN request time: 0.514s | source
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cluckindan ◴[09 Mar 25 06:34 UTC] No.43306791[source]▶
”I’ve long found that tea makes me much less nervous than coffee, even with equal caffeine.”

Well, of course you are less nervous when you avoid taking coffee: it contains a LOT of beta-carbolines which act as MAO-A inhibitors. MAO-A inhibition directly prevents adrenalines from being inactivated by oxidation.

replies(3): >>43306823 #>>43306880 #>>43307405 #
1. cubefox ◴[09 Mar 25 06:41 UTC] No.43306823[source]▶
Or maybe it doesn't actually make him less nervous, in which case the beta-carbolines are irrelevant.
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2. cluckindan ◴[09 Mar 25 14:02 UTC] No.43309119[source]▶
Of course. MAO A/B producing gene variants (including high- and low-activity VNTRs and even complete deletion) are some of the most varied in humans.