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817 points dynm | 3 comments | | HN request time: 0.02s | source
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baby ◴[] No.43306343[source]
I tried it and it never did anything, I tried all sorts of CBD products as well (while in SF) and I never noticed a thing.

The only thing that worked was microdosing shrooms which I've done twice in SF. I felt very calm and had a lot of novel ideas during these two days. Would recommend trying. Never microdosed LSD.

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1. kerkeslager ◴[] No.43306726[source]
The thing is, if you're looking for an obvious effect like the classic psychedelics have, you're going to be disappointed with most mood treatments.

That doesn't mean they don't work--it might be because you didn't measure whether it worked effectively.

A lot of people (but not all people) say that exercise doesn't improve their mood, but when you ask them mood related questions when they aren't thinking about exercise, it becomes clear that exercise massively effects mood.

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2. baby ◴[] No.43320621[source]
If it has such a negligible effect then what's the difference with just taking a placebo? Might as well no?

I've never met anyone who think exercise doesn't make them feel good on the other hand

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3. kerkeslager ◴[] No.43339733[source]
> If it has such a negligible effect then what's the difference with just taking a placebo? Might as well no?

Who said they were negligible? I didn't. I said you might not have measured the effects effectively. That doesn't mean they're negligible.

Anxiolytics generally have the problem that people notice/remember when they're anxious, but don't notice/remember when they're not anxious. As a result, when you track someone's anxiety attacks who is on an anxiolyitic, you might see, say, a 80% reduction in frequency, but that that person won't remember all the times they didn't have anxiety attacks, they remember the times they had anxiety attacks, and they may conclude that the anxiolytic didn't work if they weren't actually tracking carefully. Notably, there's a growing body of actual scientific research that CBD is effective for treating anxiety, but the effect you report, "It didn't do anything" is almost universal from people who try it.

Non-scientific "experimentation" with CBD is that a lot of people take it hoping to get high, and when it doesn't get them high, they conclude it has no effect. But in fact CBD does have effects, it just doesn't have the effects the self-experimenter was looking for.

Psychedelics have the opposite research problem: they very much do get you high. So people take it for some pretense like treating anxiety, and then when it gets them high, they believe it treated their anxiety whether it did or not, because at least it did something obvious.

I'm not saying psychedelics don't treat anxiety, I'm simply saying that self-experiments which don't attempt to control for these problems generally aren't very good proof of anything.

If you want my personal opinion, I think the evidence for CBD as an effective anxiolytic is stronger than the evidence for psilocybin as an anxiolytic, although I think both need more research to be conclusive.