I have very slight astigmatism. I don't wear glasses when I ride my motorbike because they're a pain with the helmet. I don't have issues, but when I drive a car, I usually wear them. The difference is that I can see traffic signs much further away, especially at night. I do wear them when working at the computer, since I find they help with eye strain, but I do like using high-definition displays and prefer my text an widgets on the smaller side.
I only ever get blurry vision after very long days in front of the computer without doing anything else (think 12-14 hours). I doubt this is glasses related, since I remember having this issue while studying late as a child, and at the time I had perfect vision (which lasted until my late twenties when my ophthalmologist suggested glasses would be a good idea).