Whether the EIC of SciAm overstepped with her own editorializing is probably not something we as outsiders can really say, given the complexities of running a newsroom. I would caution people against taking this superficial judgment too seriously.
Whether the EIC of SciAm overstepped with her own editorializing is probably not something we as outsiders can really say, given the complexities of running a newsroom. I would caution people against taking this superficial judgment too seriously.
https://www.scientificamerican.com/article/what-are-puberty-...
The “side” (scare quotes, for there are multiple positions available, not just those that come through the lens of US politics) with the higher quality analysis is that expressed in the Cass Review, which does not call for a ban, but rather for clinical trials and a data linkage study (for which data linking adult outcomes to pediatric gender interventions has so far been withheld by the relevant clinics - draw your own conclusions about why they would not want that to be surfaced).
The Cass Review itself offers no evidence the blockers are dangerous or inevitably irreversible (or if one takes a less cautious approach, cause patients more problems with irreversibility than not using them), merely finding that only two papers providing evidence for the treatment being safe and optimal were of "high quality" with others being of "moderate" quality or "low" quality and calling for another trial. It did not find higher quality papers drawing opposing conclusions. People more knowledgeable and cynical than me have suggested that treatments for other, less politically-charged but complex conditions may also suffer from the literature that supports clinicians preferred approach being of "moderate" quality but seldom face shutdown as a result. The side that trumpeted this conclusion (because it very much is political, even in the UK) delightedly concluded that as the favourably-disposed evidence mostly fell short of excellence, all gender affirming care must be shut down permanently. Perhaps you view things differently and would very much like to see the new clinics opened and a clinical trial designed to Ms Cass' liking devised, but it's safe to say most of the people trumpeting it as the last word in the debate would not.
quote 1: “These puberty-pausing medications are widely used in many different populations and safely so,” McNamara says.
quote 2: “From an ethical and a legal perspective, this is a benign medication,” Giordano says. She is puzzled by the extra scrutiny these treatments receive, considering their benefits and limited risks. “There are no sound clinical, ethical or legal reasons for denying them to those in need,” she says.
quote 3: Like any medication, GnRHas carry the potential for adverse effects.
Now if you read one of the studies they link (https://pmc.ncbi.nlm.nih.gov/articles/PMC7497424/).
quote: "Arguments against the use of GnRHa that have been raised include possible long-term adverse effects on health, psychological, and sexual functioning (Laidlaw, Cretella, & Donovan, 2019; Richards, Maxwell, & McCune, 2019; Vrouenraets et al., 2015)."
I really feel like they overstate the strength of their positions with the articles they cite. All of them show clear limitations of the results which clearly show we need more data.