Anything but blind applications. I know that's not useful information for a lot of people, but if you have experience, you _really_ need to lean on ex-coworkers that you had a good relationship with. Any way to not be a random resume is going to exponentially help your chances.
Additionally, depending on how desperate your search is, you need to be honest with yourself about remote work being a requirement. Ideally you shouldn't budge on it, but the reality is that capital owners have the leverage now vs a few years ago, and you have to play the game. But I would only budge on this if you absolutely need a job asap.