I'd like to see Apple run some opt-in scientific trials.
For example: Does active noise cancellation result in more or less hearing loss?
Or Alcohol consumption: Apple Health could ask each day how many drinks you had and many people want to track it anyway. Correlate that to health metrics at a wide scale. It'd be much more powerful than any currently existing study given the userbase likely to opt-in.
Let people see exactly the data that will be uploaded prior to consenting to alleviate any privacy concerns. They already have stronger data-protection and anonymity mechanisms than those used by most studies built directly into the phone.
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