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Energy-based model explains how chronic stress transforms into disease over time

(www.sciencedirect.com)
181 points andrewstetsenko | 3 comments | 20 Oct 24 14:32 UTC | HN request time: 0.228s | source
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hammock ◴[20 Oct 24 16:15 UTC] No.41896355[source]▶
This paper reminds me of the “insight” / factoid that all mammals are basically born with the same rough number of heartbeats, and then they die. Smaller animals like mice have shorter lifespans and faster heartbeats. Larger ones like whales and elephants have slower heartbeats and longer lives.

The humorous (and obviously false, though apparently not if this paper is out there) corollary is that any exercise and non-sedentary lifestyle means you lose years of your life

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1. mcoliver ◴[20 Oct 24 17:44 UTC] No.41897099[source]▶
Haven't done the math but maybe they aren't so disconnected. If I can trade off an elevated heart rate of 170 for an hour every day or two in exchange for dropping my resting heartbeat from 70 to 50, I should end up with more years to use those finite heartbeats. As with most things in life it's about balance. Extremes and absolutes in most everything tend to result in poor outcomes. You don't want to be sitting 24/7 or running 24/7.
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2. ◴[20 Oct 24 19:27 UTC] No.41897854[source]▶
3. hammock ◴[20 Oct 24 23:45 UTC] No.41899476[source]▶
Starting with 60 RHR:

+120 bpm for 60min = -7200 beats off your life -20 bpm for 23 hours = +27600 beats added to your life Net: +20400 beats, or 6.8 hrs added, every day you keep it up

Obviously some factors missing in that, you can't live forever.. but back of the envelope it nets positive not negative