←back to thread

Type 2 diabetes: New treatment eliminates insulin for 86% of patients

(scitechdaily.com)
286 points amichail | 1 comments | 17 Oct 24 20:46 UTC | HN request time: 0.213s | source
Show context
janice1999 ◴[17 Oct 24 21:24 UTC] No.41873971[source]▶
Paper: https://pubmed.ncbi.nlm.nih.gov/38692517/

> Recellularization via electroporation therapy (ReCET) is a novel endoscopic procedure that uses electroporation to induce cellular apoptosis and subsequent reepithelization.

replies(1): >>41873977 #
arcticbull ◴[17 Oct 24 21:26 UTC] No.41873977[source]▶
... plus GLP-1.

GLP-1s baseline eliminate insulin for about ~40% of people. This boosts that number to 86%.

Note that Tirzepatide also reduces the chance of developing type 2 in the first place by 94%, and I suspect that newer generation receptor agonists will see higher insulin discontinuation rates in general.

Very cool stuff all around. Might finally be able to put this whole obesity-and-diabetes thing to bed.

replies(1): >>41874242 #
metadat ◴[17 Oct 24 21:58 UTC] No.41874242[source]▶
Tirzepatide side effects sound pretty nasty, though less so than dying in a diabetic coma.

https://en.wikipedia.org/wiki/Tirzepatide

replies(4): >>41874264 #>>41874320 #>>41874776 #>>41881289 #
1. consteval ◴[18 Oct 24 17:00 UTC] No.41881289[source]▶
Dying in a diabetic coma is just one thing. Diabetes and other metabolic disorders are all very closely related. We're talking dozens of severe, deadly, and lifespan reducing illnesses. Odds are if you're diabetic long term you're also obese, and have atherosclerosis, and high blood pressure, and high cholesterol, etc.