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232 points BostonFern | 1 comments | | HN request time: 0.661s | source
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itronitron ◴[] No.41856291[source]
>> the person has symptoms provoked by gluten, but they don’t have evidence of celiac disease

Sigh, it would be useful to know what specific tests for celiac were performed that came back inconclusive or even just stating what doctors consider to be definitive evidence of celiac disease.

replies(3): >>41862694 #>>41863234 #>>41864369 #
1. macobrien ◴[] No.41862694[source]
When I was diagnosed back in the mid 00s, the tests were:

- A blood test for elevated levels of tTG-IgA antibodies, which are produced by the celiac autoimmune reaction. This has something like a 5% false negative and 10% false positive rate, so it's generally a strong indicator but doesn't totally confirm the diagnosis. - An EGD/biopsy of the small intestine. The lining of the small intestine is damaged by anti-tTG antibodies in a way that's recognizable under a microscope.