I would wager that over the last several decades BLAST (basic local alignment search tool) has done more to advance our knowledge of biology than any other algorithm.
https://bioinformaticsreview.com/20210503/how-blast-works-co...
"The heart of many well-known programs is a dynamic programming algorithm, or a fast approximation of one, including sequence database search programs like BLAST..."
This reminds me of biologists bickering about what is or is not a gene, and endless snorefests of ontologists bickering about the semantics of a label on an edge in a graph.
It was not amusing then either.