Tailscale can certainly be blocked on NGFW firewalls like Palo Alto. I am not a BOFH, but also can’t have random employees circumventing security policies by setting up tailscale and leaving permanent backdoors in my corporate network.
I remember the good old days when everyone had a public IP on the Internet and how easy it was to setup things. It was cool and fun while it lasted. But now things are different and security is a nightmare when we have to deal with things like ransomware.