One major effect of this is that weed stores will be able to use banks and payment processors legally once the regulators catch up.
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(Call me crazy and old-fashioned, but I don't think I'd want 50+ illegally-correlated transactions on my financial record that the government could lump into other charges...)
DEA isn't kicking down doors to bust dudes doin 'roids, mostly nailing low-hanging fruit like doctors who blatantly spam fake steroid prescriptions