One major effect of this is that weed stores will be able to use banks and payment processors legally once the regulators catch up.
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Also, it doesn't seem like it would be that hard to find someone to accept it as payment, since they can convert it to cash too. And the sort of landlords/suppliers/employees willing to do business with a dispensary seem like exactly the sort who would accept Bitcoin.
If you're going through all that hassle, it's much easier just to be a cash-only business in the first place.
Keep it in a safe somewhere undisclosed instead of a retail storefront everybody knows is holding a ton of cash, or spend it.
The point is that it moves the cash from the publicly visible location to somewhere nobody knows to rob.