"According to the theory of cosmic inflation initially introduced by Alan Guth and D. Kazanas, if it is assumed that inflation began about 10−37 seconds after the Big Bang and that the pre-inflation size of the universe was approximately equal to the speed of light times its age, that would suggest that at present the entire universe's size is at least 1.5×1034 light-years—at least 3×10^23 times the radius of the observable universe."
So, if true, all those metrics of atoms, stars, planets in the known universe are multiplied by 10^23.
Even if intelligent life were rare enough to only appear once per knowable universe, there could be 10^23 different intelligent species - single planet to galaxy spanning empires - that would probably never meet another intelligent species (except those with the same ancestors).