It's what's so annoying with people arguing about "something from nothing."
Even a vacuum has zero point energy. The idea that there could even be 'nothing' at any point in time is arguably a bigger leap of faith than the notion of some deity for whose sake it is being argued as a presupposition.
"It's all in your head" might be one answer but that's the question, what plane or dimension is it? and why do we not see it anywhere externally?
This question could be applied to a number of things historically, and may even be in effect going forward.
http://www.av8n.com/physics/black-box.htm#sec-plane-of-exist...
(Which made me realize how little I know about eastern mysticism...)