The company failed for multiple reasons and some of those were a result of sexism. So, I wouldn't say it was the sole cause for their decline.
> She told Harp that one man had complained to her about “the awful bitch who was running the company."
While Jobs and to some extent Gates were called eccentric geniuses for all their misdeeds in their early years, I have no doubts on what Harp & Ely would be called if they attempted to do even half of the bad things Jobs and Gates did.