I use Qubes because of one exact feature: single Desktop Environment for windows from different Virtual Machines. And AFAIK there are no alternatives.
Use it for work, development, personal tasks for about 2 years so far.
But it has many restrictions, e.g. gaming is problematic because of this single "main" desktop and trucking cursors bug, recording screen when there are several monitors is bugging and problematic, streaming or working with graphics is problematic, development that requires other virtualization like android (as i heard) is problematic (though docker works, tested).
This OS is enough for my tasks, I like concept of separating activities, e.g. when i share desktop on skype, people see only skype's VMs windows. And single Desktop Env is killer feature.
But because of many restrictions this OS is definitely not for everyone.
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