If these keys are leaked, they should be adopted by open source projects to disable secure boot.
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Even if you were to completely replace all of the signatures with your own, you are going to have to trust some of the MS/manufacturer ones (unless you replace all the manufacturer-signed firmware modules with your own).
... of which there might not be any. Eg none of my half-dozen SB-using systems (desktops and laptops) have anything in the ESP other than the booloader and UKIs I put there, and boot with my own keys just fine.