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851 points swyx | 3 comments | | HN request time: 0.622s | source
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eightysixfour ◴[] No.25827086[source]
I remember reading this the last time and it was posted and I still think the core failure is that the author didn't actually recognize the issue he was solving. He thought the problem was choosing the most effective medicine when the real problem was decision fatigue looking at endless shelves of things that all seem to do the same thing. Those two problems sort of look the same, but the latter cannot be resolved by selling the tool to doctors in their offices.

The tool should have been designed (IMO) as a consumer tool, either a kiosk at CVS/Walgreens/pharmacies to assist with OTC med selection or possibly as a website with ads/referrals. I would absolutely choose a pharmacy over another as a result of them having something to help through that process, especially when I have a headache.

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ihumanable ◴[] No.25827591[source]
I'm grateful for this comment because it put into words the thing I couldn't.

I'm reading the epiphany part of this post, to quote:

You have a mind-shattering headache. You're standing in the aisle of your local CVS, massaging your temples while scanning the shelves for something—anything—to make make the pain stop.

What do you reach for? Tylenol? Advil? Aleve?

Most people, I imagine, grab whatever's cheapest, or closest, or whatever they always use. But if you're scrupulous enough to ask Google for the best painkiller, here's how your friendly neighborhood tech behemoth would answer:

[Screenshot of Google Search Results]

Oh thanks Google that's just all of them.

---end quote---

The author immediately identifies that this isn't a real problem, by their own admissions that "Most people, I imagine, grab whatever's cheapest, or closest, or whatever they always use." Yea, most people when they have a headache and know that most painkillers on the market will result in about the same degree of relief, don't bother to cross reference a medical meta-analysis, because they have a headache and if the $0.01 worth of aspirin doesn't make it feel better they will just take a second pill and eat the penny.

I like the author's conclusion about how to quickly validate business ideas, but even in the title the author still holds firm to the belief that this was a "fantastic startup idea" even though reality seems to think otherwise. Was this such a great idea, do most consumers actually want to review a meta-analysis when picking their OTC medicine, or do most people just try a few things, get influenced by advertising, and purchase the most reasonably priced medicine they think will help. I am just a single data point, but I don't normally feel naked and unscrupulous when I just read the symptoms that a medicine treats and pick one, and that strategy generally works just fine.

Solution in search of a problem and also in search of humans that act in this weird atypical fashion.

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PeterisP ◴[] No.25827683[source]
Waiit - "You have a mind-shattering headache. [..] What do you reach for? " - isn't this where you're supposed or even required to ask the pharmacist? You know, the person who has the years-long training to know drug effects, limitations and interactions with other drugs?
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eightysixfour ◴[] No.25827788[source]
I'd say yes but the last time I was truly sick (flu) my roommate went to the store and asked the pharmacist what to give me and came back home with a bunch of homeopathic sugar pills. My trust in other humans is pretty low for this sort of stuff.
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perl4ever ◴[] No.25829620[source]
For some reason, people seem to have evolved to consider nicotine products (for instance) more opposed to the abstract mission of a drugstore than homeopathic products.

I have never smoked or vaped or anything, but it's the homeopathic OTC meds that viscerally upset me, that they should be allowed on the shelves.

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1. jacobion ◴[] No.25832307[source]
Isn't there a social benefit in letting the 10% (or whatever) of people that believe in them get a safe and effective placebo, for many conditions where that's all that's needed?
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2. perl4ever ◴[] No.25837025[source]
I see belief in the "placebo effect" as a mind virus. Because it is not just a justification for lying to patients, but entails medical people lying to themselves.

I get tired trying to explain, and if I'm not convincing anyone, maybe it's me who doesn't understand...but, I feel like the key is to ask yourself, if the placebo effect is something that you can scientifically demonstrate, how would you arrange a control group?

Failure to identify a reason for an apparent effect cannot be turned into proof that "nothing" has an effect. It's just a mental short circuit that people get trapped in.

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3. jacobion ◴[] No.25841457[source]
> if the placebo effect is something that you can scientifically demonstrate, how would you arrange a control group?

Easy, just don't give the control group any medicine. Give the other group a placebo. If outcomes are better for the second group, it's evidence that placebos work, just as clearly as the usual trial provides evidence that medicines work.