Why HN was slow and how Rtm fixed it

Since no one has mentioned it yet - Varnish-cache.org, written by a FreeBSD kernel hacker, has a very nice feature, in that it will put all overlapping concurrent requests for the same cacheable resource "on hold", only fetch that resource once from the backend, then serve the same copy to all. Nearly all the expensive content on HN would be cacheable by varnish. Then you can get it down to pretty close to "1 backend request per content change" and stop worrying about how arbitrarily slow the actual backend server is, how many threads, how you deal with the socket, garbage collection, and all that.

Can't you only use varnish for mostly non-dynamic content? Like for example, wouldn't the fact that it displays my username and karma score at the top of the page make it so that you couldn't use varnish (or at least make it more difficult)?

Yes, you'd have to somehow separate the dynamic content from the static content so they could be fetched in different requests and then combined (probably via ajax). If it's just your username and karma then it's simple enough, but if the comments are displayed differently for different people then it could be bear.