But wait they're just about to get AGI why would he leave???
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The only other thing I can imagine is not very charitable: intellectual greed.
It can't just be that, can it? I genuinely don't understand. I would love to be educated.
Currently one of the key issues with a lot of fields is that they operate as independent / largely isolated silos. If you could build a true AGI capable of achieving top-level mastery across multiple disciplines it would likely be able to integrate all that knowledge and make a lot of significant discoveries that would improve people's lives. Just exploring existing problem spaces with the full intellectual toolkit that humanity has developed is probably enough to make significant progress.
Our understanding of biology is still painfully primitive. To give a concrete example, I dream that someday it'll be possible to develop medical interventions that allow humans to regrow missing limbs and fix almost any health issue.
Have you ever lived with depression or any other psychiatric problem? I think if we could create medical interventions and environments that are conductive towards healing psychiatric problems, that would also be a massive quality of life improvement for huge numbers of people. Do you know how our current psychiatric interventions work? You try some drug, flip a coin to see if it does anything and wait 4 weeks to get the result. Then you keep iterating and hope that eventually the doctor finds some magical combination to make life barely tolerable.
I think the best path forward for improving humanity's understanding of biology, and ultimately medical science, is to go all-in on AGI-style technology.