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589 points gmays | 1 comments | | HN request time: 0.198s | source
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cyberdrunk2 ◴[] No.45772428[source]
I wonder if this could help explain why creatine helps mitigate the effects of sleep deprivation. Since creatine aids in water retention.

https://pubmed.ncbi.nlm.nih.gov/16416332/

replies(3): >>45772453 #>>45772678 #>>45774367 #
1. Citizen8396 ◴[] No.45774367[source]
I would imagine it has more to do with its principal function in recycling ADP back to ATP (fuel for cells). People who are sleep deprived also have impaired glucose metabolism, meaning that the cellular "fuel pipeline" is impeded. Perhaps creatine is especially helpful under these conditions.

https://pmc.ncbi.nlm.nih.gov/articles/PMC1991337/