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589 points gmays | 7 comments | | HN request time: 0.418s | source | bottom
1. JumpCrisscross ◴[] No.45773796[source]
Could ADHD be caused by a broken flushing response? Lots of flushing followed by intense focus caused by the tabula rasa?
replies(5): >>45774023 #>>45774167 #>>45774326 #>>45774577 #>>45785892 #
2. delecti ◴[] No.45774023[source]
I'm not an expert, but that wouldn't really fit with my understanding of ADHD. It's not that we have a lack of attention ("defecit" of attention, as the name suggests), it's an impaired ability to direct it.

To abuse a metaphor, the sleep-deprivation-induced spontaneous CSF flush is slamming on the brakes of a car, and ADHD related attention shifts would be more like a drunk toddler is turning the steering wheel wherever they please, but the gas/brakes still work fine.

3. luciferin ◴[] No.45774167[source]
I suppose it's possible, but it seems less likely to me because ADHD is a life long neurodevelopmental disorder that shows [visible physical changes in the brain on scans](https://pmc.ncbi.nlm.nih.gov/articles/PMC7879851/). That said, there are statistically more people with narcolepsy who have ADHD, and the same goes for sleep apnea. There's a number of hypotheses I've read as to why, to name a couple: related epigenetic causes, or [possible misdiagnosis](https://pmc.ncbi.nlm.nih.gov/articles/PMC7336577/) (narcolepsy is much harder to diagnose than ADHD if you don't have textbook symptoms). So there is definitely something there.
replies(1): >>45774741 #
4. Citizen8396 ◴[] No.45774326[source]
Disordered sleep can cause executive dysfunction similar to ADHD, but it does not cause ADHD. It certainly can exacerbate it or be diagnosed incorrectly.
5. Geee ◴[] No.45774577[source]
Not sure if it's related, but I have way more ADHD-like symptoms if I'm on late sleep schedule, but sleeping the same amount of hours.
6. ◴[] No.45774741[source]
7. mpascale00 ◴[] No.45785892[source]
Even if this is a possible factor it most certainly would not be the only cause.