Schizophrenia is the price we pay for minds poised near the edge of a cliff

I have schizoaffective disorder, induced by a bad trip from marijuana. It was like the 3rd time I had tried weed, and I naively took too much.

For me psychosis feels like pattern matching going on extreme overdrive, while at the same time memory goes to shit. It's truly an awful illness, and what's worse is that the current medical treatments are bad. I've been fortunate enough where I can get by on a low dose olanzapine, but for many people they simply don't work at all.

Even though I'm doing well enough to function normally and hold down a good, well paying job, it's impossible to find a partner. If I were to have kids, I would have to go through one of the embryo prescreening services. I am strongly in support of these screening services - the disease is truly horrible.

There has been little progress on treatments for schizophrenia, the mechanism of action of these drugs has remained the same for decades. The side effects are almost as bad as the disease, which is why so many schizophrenic stop taking them. The only novel medication recently released is Cobenfy, which I have not tried yet.

Personally I am holding out hope that schizophrenia has some basis as an autoimmune disease. There was a cancer patient who had a bone marrow transplant and ended up being cured: https://www.nytimes.com/2018/09/29/opinion/sunday/schizophre...

I have family with that.

The most striking thing, is the absolute certainty of the thinking. They feel as if their thinking is crystal-clear, and that they are the only one that "sees the patterns."

Currently, they're doing well. I know of others, that are not so fortunate.

It seems that pot is about the worst thing that a schizoaffective/schizophrenic person can use. They are better off chewing tabs of acid. I've not used it in about 45 years, and I've heard that today's pot is a heck of a lot stronger than what I remember.

Can I ask how you are sure they haven’t had some novel insight that you just don’t currently understand? Like maybe they are bad at explaining but whatever pattern they noticed is valid?

I’m not defending them as I don’t know any details, I’m just curious how you came to be certain about your assessment.

I can't speak for the above person, but what the OP of this comment thread said also tracks with my own experience of schizoaffective disorder: when I'm psychotic, the pattern matching part of my brain goes into overdrive and not only does my brain erroneously fill in the blanks in sensory input (causing hallucinations), it does the same thing on an abstract or logical level with ideas and people. It's easy to fall into the trap of paranoid delusion when you feel like you're seeing connections between so many otherwise benign, disconnected things and events.

I think what really gets me is that despite my constant vigilance and skepticism toward my own thoughts, I simply cannot talk myself out of how truly real those delusions feel when they happen. I can even acknowledge how absurd they are, even in the moment, but I can never shake the feeling that they're still very, very real. It's so maddening. The best I can do is to just not act on those thoughts.

Maybe the above person's family is actually unearthing valid insights, but if they're prone to psychosis, in that state they'll be prone to finding connections, associations, patterns, and so on between things in a way that doesn't hold up to scrutiny. It'll feel very real to them in the moment, but when they exit that state (if they do) they'll likely be on the same page as others in thinking those ideas were a stretch.