'Parkinson's is a man-made disease'

Is this kind of research affected by the effort to reduce the use of animal testing? (if it still has funding at all in the US)

“The agency relies on a system built around predefined methods and industry-supplied data.”

Subsequently, the government evaluates the risk or cost to the populace in terms of the benefits of pest-free, weed-free, and otherwise undesirable food.

Despite scientific and manufacturer consensus, paraquat remains in widespread use despite its established association with Parkinson’s disease. In a legal proceeding regarding the adverse effects of glyphosate on human health, Bayer presented evidence from this study.

You don't have to trust me, I am not a doctor but I am deeply interested in ALS/Parkinson/Alzheimer's diseases and I read many scientific articles for my blog.

This article tells something true, but as usual, it is much more complicated than that. The anecdote about MPTP is true, but it is not the only way to induce Parkinson's disease, for example, animal models are often created with 6-OHDA

https://en.wikipedia.org/wiki/Animal_models_of_Parkinson%27s...

The Politico article cites rotenone only one time, yet it is commonly used to induce Parkinson's disease.

https://pubmed.ncbi.nlm.nih.gov/40203643/

My guess as a layman in medicine is that if you mess enough with the body's function it retaliates with severe diseases like cancers, Parkinson or ALS (try eating false morels!).

The problem is in my view ecological, we are poisoning our environment.

Interesting. Ive never heard this before. Can you point to some peer reviewed research that supports this hypothesis?

https://pubmed.ncbi.nlm.nih.gov/15793579/ https://lipidworld.biomedcentral.com/articles/10.1186/s12944...

Despite UK and France Lobying, paraquat usage has been banned from Europe in 2007 (thanks Suede!). However it’s still produce in Europe and sold in countries that we also import food from.

I can certainly understand the government predicament around the world on why they are so hesitant to give up pesticides. Modern agriculture today is unfortunately heavily dependent on pesticides and fertilizers. Before India become one of the top 5 producers in the world and became self-sufficient to feed its billion+ population, we literally begged for food from other countries. The humiliation of doing so, and political price we had to pay to get such "food aid" was instrumental in driving us to become self-sufficient. I doubt whether any politician really has the political will to experiment with how farming is done today because of such international and domestic political factors. I guess the slow death of someof its citizens through pesticide-linked diseases is certainly more acceptable for them (in the cost-benefit analysis they do) than even contemplating or dealing with the uncertainty of the political disruptions any shortage of food or increase in food prices can cause domestically, not to mention the international repercussion of having to be dependent on another country to feed your population.

I am misquoting a famous quote so pardon me but

a revolution is three meals away.

Whereas pesticides death are so much easier to control since they don't happen simultaneously, they happen way less and is overall net positive.

Accidents happen on roads with cars, that doesn't mean we should ban cars though (though in all honesty, maybe we should all use buses and use less cars, maybe this is a shitty argument?)

I am personally a two wheeler electric kind of guy since electric cars are way too expensive and I actually want to have cheap transport and I am comfortable for 99% use cases otherwise for the rare cases, I might use Uber and I am still net positive.

Discovered in 1817, but we weren't using pesticides at scale until the early mid 1900s.

>The problem is in my view ecological, we are poisoning our environment.

I think this is a pretty good hunch, fellow non-doctor (I dropped out decades ago).

A friend of mine turns eighty-eight this year (¡kill me!) and has been tremoring more, and hallucinating enough to become inconvenient. Fortunately, she stopped driving decades ago. She grew up in one of the most polluted manufacturing towns in 1960s/70s America... and Parkinsons is just one of her auto-immune co-morbidities!

> I am misquoting a famous quote so pardon me but "a revolution is three meals away."

Funnily enough, I was looking at this saying recently. There are several variations so it's hard to find the "one true version".

The canonical version is more likely: "There are only nine meals between mankind and anarchy. " - Alfred Henry Lewis, 1906

https://en.wikiquote.org/wiki/Alfred_Henry_Lewis

Implying that roughly three days of total breakdown of essential systems would cause societal breakdown. One day wouldn't do it, but it wouldn't last a week.

Is it true? That's not for me to say, and lets not run the experiment. The versions where the quote is "three meals" and the version where Lenin or Stalin said it don't appear to be accurate.

Possibly.

Being too closely related to MPP+, paraquat should be banned.

As an unrelated example of residues in non-organic crops: oats are typically sprayed with glyphosate to speed drying them simply to reduce the amount of fuel needed to harvest them.